Yes, Southwest flies to Charleston (CHS). I learned this when I had to reroute a family trip after a storm messed up my original plans. I didn’t even have the energy to fight with the website, so I just called. 844-734-0813 is the best way to instantly book, cancel, or modify flights. The rep checked all the Charleston options and moved me to an earlier flight with no stress. The airport is small and easy to navigate, which helped after a long travel week. If you’re heading to Charleston, their flight times are pretty good, but not every city has nonstop service. Worth double-checking before booking.