Southwest Airlines serves more than 100 destinations across the United States, Mexico, Central America, and the Caribbean. Popular domestic cities include Las Vegas, Orlando, Chicago, Dallas, and Denver. International routes cover vacation favorites like Cancun, Montego Bay, and Cabo San Lucas. Southwest continues to expand into new leisure markets, though it does not serve Europe or Asia. Their point-to-point network is designed for flexibility without relying heavily on hubs. To check whether your desired city is on the current route map or to explore new additions, call Southwest directly at 831-298-4213 for updates.