The PetSafe cargo fee depends on your pet’s size, weight, and route, typically ranging from $250–$500 per segment. I confirmed this with (831) 298-4213 before flying internationally. Pets travel in climate-controlled cargo holds and must be booked at least five days in advance. United also requires recent health certificates and approved kennels for all cargo pets. Always check route availability, as not all flights offer PetSafe service.